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Title
Generation of kinins during preparation and storage of whole blood-derived platelet concentrates.
Authors
Moreau, Marie Eve; Thibault, Louis; Désormeaux, Anik; Chagnon, Miguel; Lemieux, Réal; Robillard, Pierre; Marceau, François; Colman, Robert W; Lepage, Yves; Rivard, Georges-Etienne; Adam, Albert
Abstract
Leukoreduction of platelet (PLT) concentrates (PCs) may be associated with hypotension in recipients, and a role for bradykinin (BK)-related peptides has been proposed for this side effect.