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- Title
Current Literature Are the Effects of Stimulation Catching?
- Authors
Lesser, Ronald P.
- Abstract
Anschel DJ, Pascual-Leone A, Holmes GL Neurosci Lett 2003;351:9–12 The cerebrospinal fluid (CSF) of animals exposed to electroconvulsive shock (ECS) has anticonvulsant properties when injected into naive animals. The present study investigated whether the CSF of humans exposed to 1- or 10-Hz repetitive transcranial magnetic stimulation (rTMS) has similar properties. By using a 4-day rat flurothyl-kindling seizure model, we found that the kindling rate was significantly decreased by intraventricular injection of CSF from depressed patients exposed to 1-Hz rTMS. The CSF from patients that underwent 10-Hz rTMS showed a trend toward an increased kindling rate. These results support the similarity of ECS and rTMS and suggest that 1-Hz and 10-Hz rTMS produce distinct physiologic changes.
- Publication
Epilepsy Currents, 2004, Vol 4, Issue 3, p116
- ISSN
1535-7597
- Publication type
Academic Journal
- DOI
10.1111/j.1535-7597.2004.43011.x