We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
ALDH2 and ADH1B interactions in retrospective reports of low-dose reactions and initial sensitivity to alcohol in Asian American college students.
- Authors
Luczak, Susan E; Pandika, Danielle; Shea, Shoshana H; Eng, Mimy Y; Liang, Tiebing; Wall, Tamara L
- Abstract
A mechanistic model has been proposed for how alcohol-metabolizing gene variants protect individuals from the development of alcohol use disorders, with heightened sensitivity to alcohol being an early step (endophenotype) in this model. This study was designed to determine whether possession of 2 alcohol-metabolizing genes variations, the aldehyde dehydrogenase ALDH2*2 allele and the alcohol dehydrogenase ADH1B*2 allele, was associated with self-reported sensitivity to alcohol at low doses and at initial use.
- Publication
Alcoholism, clinical and experimental research, 2011, Vol 35, Issue 7, p1238
- ISSN
1530-0277
- Publication type
Journal Article
- DOI
10.1111/j.1530-0277.2011.01458.x