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- Title
Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice.
- Authors
Mulligan, Megan K; Rhodes, Justin S; Crabbe, John C; Mayfield, R Dayne; Harris, R Adron; Ponomarev, Igor
- Abstract
Alcohol addiction develops through a series of stages, and mechanistic studies are needed to understand the transition from initial drug use to sustained controlled alcohol consumption followed by abuse and physical dependence. The focus of this study was to examine the effects of voluntary alcohol consumption on brain gene expression profiles using a mouse model of binge drinking. The main goal was to identify alcohol-responsive genes and functional categories after a single episode of drinking to intoxication.
- Publication
Alcoholism, clinical and experimental research, 2011, Vol 35, Issue 4, p659
- ISSN
1530-0277
- Publication type
Journal Article
- DOI
10.1111/j.1530-0277.2010.01384.x