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- Title
Ethanol tolerance caused by slowpoke induction in Drosophila.
- Authors
Cowmeadow, Roshani B; Krishnan, Harish R; Ghezzi, Alfredo; Al'Hasan, Yazan M; Wang, Yan Z; Atkinson, Nigel S
- Abstract
The large-conductance calcium-activated potassium channel encoded by the slowpoke gene has recently been implicated in the ethanol response. Caenorhabditis elegans carrying mutations in this gene have altered ethanol sensitivity and Drosophila mutant for this gene are unable to acquire rapid tolerance to ethanol or anesthetics. In Drosophila, induction of slowpoke expression has been linked to anesthetic resistance.
- Publication
Alcoholism, clinical and experimental research, 2006, Vol 30, Issue 5, p745
- ISSN
0145-6008
- Publication type
Journal Article
- DOI
10.1111/j.1530-0277.2006.00087.x