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- Title
Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10.
- Authors
Mandrekar, Pranoti; Catalano, Donna; White, Bernadette; Szabo, Gyongyi
- Abstract
In contrast to the deleterious effects of chronic excessive alcohol consumption on the liver and cardiovascular system, modest alcohol intake, such as 1 to 2 drinks per day, has benefits on cardiovascular mortality. Little is known about the length of time or the amounts of alcohol consumed that may cause alterations in inflammatory cells such as monocytes that are crucial to atherosclerotic vascular disease. Here, we determine in vivo effects of acute alcohol consumption on inflammatory cytokine production and nuclear regulatory factor kappaB (NF-kappaB) binding in human monocytes.
- Publication
Alcoholism, clinical and experimental research, 2006, Vol 30, Issue 1, p135
- ISSN
0145-6008
- Publication type
Journal Article
- DOI
10.1111/j.1530-0277.2006.00012.x