We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Therapeutic hotline: Primary cutaneous CD4 + small/medium-sized pleomorphic T cell lymphoma coexisting with myelodysplastic syndrome transforming into chronic myelomonocytic leukemia successfully treated with cyclophosphamide.
- Authors
Wawrzycki, Bartłomiej; Chodorowska, Grazyna; Pietrzak, Aldona; Jazienicka, Iwona; Skomra, Danuta; Kowal, Małgorzata; Dybiec, Ewa; Hercogova, Jana
- Abstract
Cutaneous T cell lymphomas other than mycosis fungoides, Sezary syndrome, and primary cutaneous CD30+ lymphoproliferations constitute less than 10% of all cutaneous T cell lymphomas. Primary cutaneous small/medium CD4+ T cell lymphoma is a member of this third group of cutaneous lymphomas, separated out as provisional entity in the World Health Organization classification - European Organization for Research and Treatment of Cancer (WHO-EORTC) classification. It still awaits development of more precise diagnostic criteria and optimal therapy. We report a case of primary cutaneous CD4 + small/medium-sized pleomorphic T cell lymphoma accompanied with myelodysplastic syndrome successfully treated with cyclophosphamide. It seems that cyclophosphamide as a single-agent chemotherapy in patients with disseminated lesions might be safe and quite effective therapeutic option.
- Publication
Dermatologic therapy, 2010, Vol 23, Issue 6, p676
- ISSN
1529-8019
- Publication type
Journal Article
- DOI
10.1111/j.1529-8019.2010.01372.x