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- Title
Targeted next generation sequencing as a diagnostic tool in epileptic disorders.
- Authors
Lemke, Johannes R; Riesch, Erik; Scheurenbrand, Tim; Schubach, Max; Wilhelm, Christian; Steiner, Isabelle; Hansen, Jörg; Courage, Carolina; Gallati, Sabina; Bürki, Sarah; Strozzi, Susi; Simonetti, Barbara Goeggel; Grunt, Sebastian; Steinlin, Maja; Alber, Michael; Wolff, Markus; Klopstock, Thomas; Prott, Eva C; Lorenz, Rüdiger; Spaich, Christiane; Rona, Sabine; Lakshminarasimhan, Maya; Kröll, Judith; Dorn, Thomas; Krämer, Günter; Synofzik, Matthis; Becker, Felicitas; Weber, Yvonne G; Lerche, Holger; Böhm, Detlef; Biskup, Saskia
- Abstract
Epilepsies have a highly heterogeneous background with a strong genetic contribution. The variety of unspecific and overlapping syndromic and nonsyndromic phenotypes often hampers a clear clinical diagnosis and prevents straightforward genetic testing. Knowing the genetic basis of a patient's epilepsy can be valuable not only for diagnosis but also for guiding treatment and estimating recurrence risks.
- Publication
Epilepsia, 2012, Vol 53, Issue 8, p1387
- ISSN
1528-1167
- Publication type
Journal Article
- DOI
10.1111/j.1528-1167.2012.03516.x