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- Title
Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy.
- Authors
Engel, Jerome, Jr; McDermott, Michael P; Wiebe, Samuel; Langfitt, John T; Erba, Giuseppe; Gardiner, Irenita; Stern, John; Dewar, Sandra; Sperling, Michael R; Jacobs, Margaret; Kieburtz, Karl; Early Randomized Surgical Epilepsy Trial (ERSET) Study Group
- Abstract
To describe the trial design for the multicenter Early Randomized Surgical Epilepsy Trial (ERSET). Patients with pharmacoresistant epilepsy are generally referred for surgical treatment an average of two decades after onset of seizures, often too late to avoid irreversible disability. ERSET was designed to assess the safety and efficacy of early surgical intervention compared to continued pharmacotherapy.
- Publication
Epilepsia, 2010, Vol 51, Issue 10, p1978
- ISSN
1528-1167
- Publication type
Journal Article
- DOI
10.1111/j.1528-1167.2010.02641.x