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- Title
Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns.
- Authors
Ogren, Jennifer A; Bragin, Anatol; Wilson, Charles L; Hoftman, Gil D; Lin, Jack J; Dutton, Rebecca A; Fields, Tony A; Toga, Arthur W; Thompson, Paul M; Engel, Jerome, Jr; Staba, Richard J
- Abstract
Current evidence suggests that the mechanisms underlying depth electrode-recorded seizures beginning with hypersynchronous (HYP) onset patterns are functionally distinct from those giving rise to low-voltage fast (LVF) onset seizures. However, both groups have been associated with hippocampal atrophy (HA), indicating a need to clarify the anatomic correlates of each ictal onset type. We used three-dimensional (3D) hippocampal mapping to quantify HA and determine whether each onset group exhibited a unique distribution of atrophy consistent with the functional differences that distinguish the two onset morphologies.
- Publication
Epilepsia, 2009, Vol 50, Issue 6, p1361
- ISSN
1528-1167
- Publication type
Journal Article
- DOI
10.1111/j.1528-1167.2008.01881.x