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- Title
Compulsory generic switching of antiepileptic drugs: high switchback rates to branded compounds compared with other drug classes.
- Authors
Andermann, Frederick; Duh, Mei Sheng; Gosselin, Antoine; Paradis, Pierre Emmanuel
- Abstract
Compulsory generic substitution of antiepileptic drugs (AEDs) may lead to adverse effects in epilepsy patients because of seizure recurrence or increased toxicity. The study objectives were (a) to quantify and compare the switchback rates from generic to brand-name AEDs versus non-AEDs, and (b) to assess clinical implications of switching from branded Lamictal to generic lamotrigine (LTG) and whether signals exist suggesting outcome worsening.
- Publication
Epilepsia, 2007, Vol 48, Issue 3, p464
- ISSN
0013-9580
- Publication type
Journal Article
- DOI
10.1111/j.1528-1167.2007.01007.x