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- Title
Cluster attacks responsive to recreational cannabis and dronabinol.
- Authors
Robbins, Matthew S; Tarshish, Sara; Solomon, Seymour; Grosberg, Brian M
- Abstract
Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subsequent use of dronabinol provided equally effective pain relief. The beneficial effect may be related to the high concentration of cannabinoid receptors in the hypothalamus, which has been implicated as a site of dysfunction in neuroimaging studies of patients with cluster headache.
- Publication
Headache, 2009, Vol 49, Issue 6, p914
- ISSN
1526-4610
- Publication type
Journal Article
- DOI
10.1111/j.1526-4610.2009.01344.x