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- Title
High-frequency cortical stimulation augments recovery of thalamocortical oscillations from hypoxia in rat brain slices.
- Authors
Kao, Chris; Forbes, Jonathan A; Stayman, Aaron; Sun, David A; Carron, Romain; Benabid, Alim Louis; Konrad, Peter
- Abstract
Cerebrovascular hypoxia results in severe impairment and electrical dysfunction of cortical and thalamic neuronal networks. Typically cellular electrical activity returns if reoxygenation is established within 5-8 min. Electrical stimulation has been shown to reduce cellular apoptosis following cerebral hypoxia in animal models and clinical case reports. In this study, we wanted to analyze the electrophysiological repercussions of electrical stimulation on recovery of spontaneous thalamocortical oscillations (TCOs) following hypoxia in a thalamocortical slice preparation.
- Publication
Neuromodulation : journal of the International Neuromodulation Society, 2011, Vol 14, Issue 2, p104
- ISSN
1525-1403
- Publication type
Journal Article
- DOI
10.1111/j.1525-1403.2011.00337.x