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- Title
H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants.
- Authors
Serkova, Natalie; Fuller, T Florian; Klawitter, Jost; Freise, Chris E; Niemann, Claus U
- Abstract
Severe ischemia/reperfusion (IR) injury is a risk factor for delayed graft function. Delayed graft function remains difficult to predict, and it currently relies primarily on serum creatinine (SCr), urine output, and occasionally on graft biopsy. (1)H-NMR (nuclear magnetic resonance spectroscopy) based metabolomics was used to establish IR-specific metabolic markers in both blood and kidney tissue. These markers were compared to SCr and graft histology.
- Publication
Kidney international, 2005, Vol 67, Issue 3, p1142
- ISSN
0085-2538
- Publication type
Journal Article
- DOI
10.1111/j.1523-1755.2005.00181.x