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- Title
Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study.
- Authors
Appenrodt, Beate; Wolf, Andrea; Grünhage, Frank; Trebicka, Jonel; Schepke, Michael; Rabe, Christian; Lammert, Frank; Sauerbruch, Tilman; Heller, J
- Abstract
Large-volume paracentesis in patients with cirrhosis and ascites induces arterial vasodilatation and decreases effective arterial blood volume, termed paracentesis-induced circulatory dysfunction (PICD), which can be prevented by costly intravenous albumin. Vasoconstrictors, e.g. terlipressin, may also prevent PICD. The aim was to compare the less expensive vasoconstrictor midodrine, an alpha-adrenoceptor agonist, with albumin in preventing PICD.
- Publication
Liver international : official journal of the International Association for the Study of the Liver, 2008, Vol 28, Issue 7, p1019
- ISSN
1478-3231
- Publication type
Journal Article
- DOI
10.1111/j.1478-3231.2008.01734.x