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Title
Toll-like receptor 4 knockout protects against anthrax lethal toxin-induced cardiac contractile dysfunction: role of autophagy.
Authors
Kandadi, Machender R; Frankel, Arthur E; Ren, Jun
Abstract
Anthrax lethal toxin (LeTx) is known to induce circulatory shock and death, although the underlying mechanisms have not been elucidated. This study was designed to evaluate the role of toll-like receptor 4 (TLR4) in anthrax lethal toxin-induced cardiac contractile dysfunction.
Publication
British journal of pharmacology, 2012, Vol 167, Issue 3, p612