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- Title
Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats.
- Authors
Kehr, J; Ichinose, F; Yoshitake, S; Goiny, M; Sievertsson, T; Nyberg, F; Yoshitake, T
- Abstract
The designer drug 1-(4-methylphenyl)-2-methylaminopropan-1-one (4-methylmethcathinone, mephedrone) is reported to possess psychostimulant, entactogenic and hallucinogenic effects. The purpose of this study was to examine the effects of acute administration of mephedrone on extracellular levels of dopamine (DA) and 5-HT in the nucleus accumbens of awake rats and compare these effects with those induced by 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and amphetamine.
- Publication
British journal of pharmacology, 2011, Vol 164, Issue 8, p1949
- ISSN
1476-5381
- Publication type
Journal Article
- DOI
10.1111/j.1476-5381.2011.01499.x