We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies.
- Authors
Doll, Christian; Konietzko, Jens; Pöll, Florian; Koch, Thomas; Höllt, Volker; Schulz, Stefan
- Abstract
Morphine activates the µ-opioid receptor without causing its rapid endocytosis. In contrast, full agonists such as [d-Ala(2) -MePhe(4) -Gly-ol]enkephalin (DAMGO) or etonitazene stimulate a rapid and profound internalization. However, the detailed molecular events underlying the differential regulation of receptor trafficking by distinct opioid agonists remain incompletely understood.
- Publication
British journal of pharmacology, 2011, Vol 164, Issue 2, p298
- ISSN
1476-5381
- Publication type
Journal Article
- DOI
10.1111/j.1476-5381.2011.01382.x