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- Title
Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice.
- Authors
Kozela, Ewa; Lev, Nirit; Kaushansky, Nathali; Eilam, Raya; Rimmerman, Neta; Levy, Rivka; Ben-Nun, Avraham; Juknat, Ana; Vogel, Zvi
- Abstract
Cannabis extracts and several cannabinoids have been shown to exert broad anti-inflammatory activities in experimental models of inflammatory CNS degenerative diseases. Clinical use of many cannabinoids is limited by their psychotropic effects. However, phytocannabinoids like cannabidiol (CBD), devoid of psychoactive activity, are, potentially, safe and effective alternatives for alleviating neuroinflammation and neurodegeneration.
- Publication
British journal of pharmacology, 2011, Vol 163, Issue 7, p1507
- ISSN
1476-5381
- Publication type
Journal Article
- DOI
10.1111/j.1476-5381.2011.01379.x