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- Title
Andrographolide regulates epidermal growth factor receptor and transferrin receptor trafficking in epidermoid carcinoma (A-431) cells.
- Authors
Tan, Y; Chiow, K H; Huang, D; Wong, S H
- Abstract
Andrographolide is the active component of Andrographis paniculata, a plant used in both Indian and Chinese traditional medicine, and it has been demonstrated to induce apoptosis in different cancer cell lines. However, not much is known about how it may affect the key receptors implicated in cancer. Knowledge of how andrographolide affects receptor trafficking will allow us to better understand new mechanisms by which andrographolide may cause death in cancer cells.
- Publication
British journal of pharmacology, 2010, Vol 159, Issue 7, p1497
- ISSN
1476-5381
- Publication type
Journal Article
- DOI
10.1111/j.1476-5381.2009.00627.x