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- Title
Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?
- Authors
Koskenvuo, Juha W; Mirsky, Rachel; Zhang, Yan; Helenius, Hans; Angeli, Franca S; De Marco, Teresa; Boyle, Andrew J; Yeghiazarians, Yerem
- Abstract
Many patients with pulmonary hypertension (PH) have symptoms of angina without evidence of occlusive coronary artery disease. For the first time, this study addresses the influence of progressively increasing pulmonary artery pressure (PAP) on left anterior descending artery flow in a rat model of PH. The role of pulmonary artery dilatation, septal wall motion abnormality, cardiac output or diastolic blood pressure in determining coronary blood flow (CBF) during PH was determined.
- Publication
Clinical physiology and functional imaging, 2011, Vol 31, Issue 6, p477
- ISSN
1475-097X
- Publication type
Journal Article
- DOI
10.1111/j.1475-097X.2011.01049.x