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- Title
Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes.
- Authors
Yu, Y; Hanssen, K F; Kalyanaraman, V; Chirindel, A; Jenkins, A J; Nankervis, A J; Torjesen, P A; Scholz, H; Henriksen, T; Lorentzen, B; Garg, S K; Menard, M K; Hammad, S M; Scardo, J A; Stanley, J R; Wu, M; Basu, A; Aston, C E; Lyons, T J
- Abstract
Increased advanced glycation end-products (AGEs) and their soluble receptors (sRAGE) have been implicated in the pathogenesis of pre-eclampsia (PE). However, this association has not been elucidated in pregnancies complicated by diabetes. We aimed to investigate the serum levels of these factors in pregnant women with Type 1 diabetes mellitus (T1DM), a condition associated with a four-fold increase in PE.
- Publication
BJOG : an international journal of obstetrics and gynaecology, 2012, Vol 119, Issue 12, p1512
- ISSN
1471-0528
- Publication type
Journal Article
- DOI
10.1111/j.1471-0528.2012.03463.x