We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Serotonin transporter promoter region (5-HTTLPR) polymorphism predicts resting respiratory sinus arrhythmia.
- Authors
Ellis, Alissa J; Beevers, Christopher G; Hixon, J Gregory; McGeary, John E
- Abstract
Respiratory sinus arrhythmia (RSA) is often conceptualized as an index of physiological flexibility that has been related to emotion regulatory capacity. Although behavioral genetics research indicates that RSA is partly heritable, relatively few molecular genetics studies have been conducted. We examined whether the serotonin transporter promoter region (5-HTTLPR) polymorphism was associated with resting RSA among healthy young adults (N=71). Short 5-HTTLPR allele carriers had significantly lower resting RSA than long 5-HTTLPR homozygotes. Genotype explained 5% of the variance in resting RSA. Although firm conclusions depend on further study, the short allele of the 5-HTTLPR polymorphism may contribute to individual differences in RSA and its behavioral correlates.
- Publication
Psychophysiology, 2011, Vol 48, Issue 7, p923
- ISSN
1540-5958
- Publication type
Journal Article
- DOI
10.1111/j.1469-8986.2010.01154.x