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- Title
A pilot study of pharmacokinetically guided dosing of oral methotrexate in the initial phase of psoriasis treatment.
- Authors
Hroch, M; Chladek, J; Simkova, M; Vaneckova, J; Grim, J; Martinkova, J
- Abstract
Clinical studies of low-dose oral methotrexate (MTX) in the treatment of psoriasis and rheumatoid arthritis document a large interpatient variability in the pharmacokinetics of MTX, including its polyglutamates (MTXPGs) in erythrocytes (RBC). This can be a factor contributing to the variability of therapeutic and toxic effects.
- Publication
Journal of the European Academy of Dermatology and Venereology : JEADV, 2008, Vol 22, Issue 1, p19
- ISSN
1468-3083
- Publication type
Journal Article
- DOI
10.1111/j.1468-3083.2007.02264.x