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- Title
The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*.
- Authors
Cozzi-Lepri, A; Paredes; Phillips, A N; Clotet, B; Kjaer, J; Von Wyl, V; Kronborg, G; Castagna, A; Bogner, J R; Lundgren, J D; EuroSIDA in EuroCoord
- Abstract
Virological failure of first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs) can compromise the efficacy of etravirine as a result of the accumulation of NNRTI resistance mutations. How quickly NNRTI resistance accumulates in patients with a delayed switch from nevirapine or efavirenz despite virological failure, when these drugs are used as a component of combination antiretroviral therapy (cART), remains unclear.
- Publication
HIV medicine, 2012, Vol 13, Issue 1, p62
- ISSN
1468-1293
- Publication type
Journal Article
- DOI
10.1111/j.1468-1293.2011.00943.x