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- Title
Inhibitory quotient as a prognostic factor of response to a salvage antiretroviral therapy containing ritonavir-boosted saquinavir. The CIVSA Study.
- Authors
Mallolas, J; Blanco, Jl; Labarga, P; Vergara, A; Ocampo, A; Sarasa, M; Arnedo, M; López-Púa, Y; García, J; Juega, J; Guelar, A; Terrón, A; Dalmau, D; García, I; Zárraga, M; Martínez, E; Carné, X; Pumarola, T; Escayola, R; Gatell, Jm
- Abstract
The addition of a low dose of ritonavir to protease inhibitors (PIs) has become a widespread strategy to improve PI pharmacokinetics. As resistance is a major barrier to long-term suppression, in salvage therapy genotype and/or phenotype scoring is currently used to predict the response. We evaluated the relationship between the saquinavir (SQV) inhibitory quotient (IQ) (virtual and genotypic) and virological response.
- Publication
HIV medicine, 2007, Vol 8, Issue 4, p226
- ISSN
1464-2662
- Publication type
Journal Article
- DOI
10.1111/j.1468-1293.2007.00464.x