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- Title
Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: a randomized placebo-controlled crossover study.
- Authors
Nielsen, S E; Persson, F; Frandsen, E; Sugaya, T; Hess, G; Zdunek, D; Shjoedt, K J; Parving, H-H; Rossing, P
- Abstract
Adding aldosterone receptor blockade to standard renoprotective treatment may provide additional renoprotection in patients with overt nephropathy. We expected an impact of spironolactone in early diabetic nephropathy, and for this hypothesis we studied the effect on markers of glomerular and tubular damage in patients with Type 1 diabetes and persistent microalbuminuria.
- Publication
Diabetic medicine : a journal of the British Diabetic Association, 2012, Vol 29, Issue 8, pe184
- ISSN
1464-5491
- Publication type
Journal Article
- DOI
10.1111/j.1464-5491.2012.03585.x