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- Title
Establishing pragmatic estimated GFR thresholds to guide metformin prescribing.
- Authors
Shaw, J S; Wilmot, R L; Kilpatrick, E S
- Abstract
Renal impairment is a contraindication to metformin treatment because of the perceived increased risk of lactic acidosis. Current guidelines define renal impairment according to the serum creatinine of the individual, but this measure is being supplanted by the use of estimated glomerular filtration rate (eGFR) as it gives a closer estimate to true GFR. This study aimed to establish pragmatic eGFR limits for use in patients being considered for metformin treatment.
- Publication
Diabetic medicine : a journal of the British Diabetic Association, 2007, Vol 24, Issue 10, p1160
- ISSN
0742-3071
- Publication type
Journal Article
- DOI
10.1111/j.1464-5491.2007.02221.x