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- Title
Re-evaluating the biological significance of seminal vesicle invasion (SVI) in locally advanced prostate cancer.
- Authors
Sapre, Nikhil; Pedersen, John; Hong, Matthew K; Harewood, Laurence; Peters, Justin; Costello, Anthony J; Hovens, Chris M; Corcoran, Niall M
- Abstract
• To examine the impact of seminal vesicle invasion (SVI) in patients with locally advanced (pT3) prostate cancer on clinical outcome. • To explore the clinical association of SVI with metastatic disease. • To distinguish between the possibilities that either seminal vesicles possess their own biological significance and represent a privileged staging site for systemic tumour cell dissemination, or that their invasion is a surrogate marker for an aggressive large-volume poorly differentiated cancer.
- Publication
BJU international, 2012, Vol 110 Suppl 4, p58
- ISSN
1464-410X
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2012.11477.x