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- Title
20-Year survival after radical prostatectomy as initial treatment for cT3 prostate cancer.
- Authors
Mitchell, Christopher R; Boorjian, Stephen A; Umbreit, Eric C; Rangel, Laureano J; Carlson, Rachel E; Karnes, R Jeffrey
- Abstract
Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? Despite a lack of randomised controlled trials, most men with locally advanced prostate cancer are recommended to undergo external beam radiotherapy (EBRT), often combined with long-term androgen-deprivation therapy (ADT). Many of these men are not offered radical prostatectomy (RP) by their treating urologist. Additionally, it is know that EBRT with long-term ADT does provide good cancer control (88% at 10 years). We have previously published intermediate-term follow-up of a large series of men treatment with RP for cT3 prostate cancer. We report long-term follow-up of a large series of men treated with RP as primary treatment for cT3 prostate cancer. Our study shows that with long-term follow-up RP provides excellent oncological outcomes even at 20 years. While most men do require a multimodal treatment approach, many men can be managed successfully with RP alone.
- Publication
BJU international, 2012, Vol 110, Issue 11, p1709
- ISSN
1464-410X
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2012.11372.x