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- Title
Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder.
- Authors
Miyamoto, Hiroshi; Yao, Jorge L; Chaux, Alcides; Zheng, Yichun; Hsu, Iawen; Izumi, Koji; Chang, Chawnshang; Messing, Edward M; Netto, George J; Yeh, Shuyuan
- Abstract
What's known on the subject? and What does the study add? Steroid hormone receptor signals have been implicated in bladder tumourigenesis and tumour progression. The expression of androgen and/or oestrogen receptors has been assessed in bladder cancer, leading to conflicting data of expression levels and their relationship to histopathological characteristics of the tumours. We simultaneously analyze three receptors in non-neoplastic bladder tissues as well as in primary and metastatic bladder tumour specimens. Our data demonstrate that the expression status correlates with tumour grades/stages and patients' outcomes.
- Publication
BJU international, 2012, Vol 109, Issue 11, p1716
- ISSN
1464-410X
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2011.10706.x