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- Title
Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study.
- Authors
Mitra, Anita V; Bancroft, Elizabeth K; Barbachano, Yolanda; Page, Elizabeth C; Foster, C S; Jameson, C; Mitchell, G; Lindeman, G J; Stapleton, A; Suthers, G; Evans, D G; Cruger, D; Blanco, I; Mercer, C; Kirk, J; Maehle, L; Hodgson, S; Walker, L; Izatt, L; Douglas, F; Tucker, K; Dorkins, H; Clowes, V; Male, A; Donaldson, A; Brewer, C; Doherty, R; Bulman, B; Osther, P J; Salinas, M; Eccles, D; Axcrona, K; Jobson, I; Newcombe, B; Cybulski, C; Rubinstein, W S; Buys, S; Townshend, S; Friedman, E; Domchek, S; Ramon Y Cajal, T; Spigelman, A; Teo, S H; Nicolai, N; Aaronson, N; Ardern-Jones, A; Bangma, C; Dearnaley, D; Eyfjord, J; Falconer, A; Grönberg, H; Hamdy, F; Johannsson, O; Khoo, V; Kote-Jarai, Z; Lilja, H; Lubinski, J; Melia, J; Moynihan, C; Peock, S; Rennert, G; Schröder, F; Sibley, P; Suri, M; Wilson, P; Bignon, Y J; Strom, S; Tischkowitz, M; Liljegren, A; Ilencikova, D; Abele, A; Kyriacou, K; van Asperen, C; Kiemeney, L; Easton, D F; Eeles, Rosalind A; IMPACT Study Collaborators
- Abstract
To evaluate the role of targeted prostate cancer screening in men with BRCA1 or BRCA2 mutations, an international study, IMPACT (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in BRCA1/2 mutation carriers and controls), was established. This is the first multicentre screening study targeted at men with a known genetic predisposition to prostate cancer. A preliminary analysis of the data is reported.
- Publication
BJU international, 2011, Vol 107, Issue 1, p28
- ISSN
1464-410X
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2010.09648.x