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- Title
Single-nucleotide polymorphisms within the antioxidant defence system and associations with aggressive prostate cancer.
- Authors
Abe, Miyako; Xie, Wanling; Regan, Meredith M; King, Irena B; Stampfer, Meir J; Kantoff, Philip W; Oh, William K; Chan, June M
- Abstract
To study the effects of oxidative stress on prostate cancer development as the exact biological mechanisms behind the relationship remain uncertain. We previously reported a statistically significant interaction between circulating selenium levels, variants in the superoxide dismutase 2 gene (SOD2; rs4880), and risk of developing prostate cancer and presenting with aggressive prostate cancer.
- Publication
BJU international, 2011, Vol 107, Issue 1, p126
- ISSN
1464-410X
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2010.09344.x