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- Title
DNA topoisomerase I and IIalpha expression in penile carcinomas: assessing potential tumour chemosensitivity.
- Authors
Berney, Daniel M; Stankiewicz, Elzbieta; Adlan, Ahmed M A; Kudahetti, Sakunthala; Biedrzycki, Olaf J; Hadway, Paul; Watkin, Nick; Corbishley, Cathy
- Abstract
To examine the tissue expression of DNA topoisomerase I (Topo I) and IIalpha (Topo II), to pursue the possibility of future chemotherapy regimens for squamous cell carcinoma of the penis (SCCP), as high expression of Topo I might indicate sensitivity to the camptothecins, whereas high Topo II might indicate sensitivity to etoposide.
- Publication
BJU international, 2008, Vol 102, Issue 8, p1040
- ISSN
1464-410X
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2008.07698.x