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- Title
A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer.
- Authors
Ryan, Charles J; Harzstark, Andrea H; Rosenberg, Jonathan; Lin, Amy; Claros, Christina; Goldfine, Ira D; Kerner, John F; Small, Eric J; Youngren, Jack F
- Abstract
To assess the tolerability of the effects of nordihydroguareacetic acid (NDGA) and its effect on prostate-specific antigen (PSA) kinetics in patients with relapsed prostate cancer, as among the many biological effects of NDGA is the inhibition of the insulin-like growth factor 1 receptor (IGF-1R) tyrosine kinase.
- Publication
BJU international, 2008, Vol 101, Issue 4, p436
- ISSN
1464-410X
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2007.07330.x