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- Title
Acute acrolein-induced cystitis in mice.
- Authors
Bjorling, Dale E; Elkahwaji, Johnny E; Bushman, Wade; Janda, Lindsay M; Boldon, Kyle; Hopkins, Walter J; Wang, Zun-Yi
- Abstract
To develop a method of direct intravesical administration of acrolein and evaluate the severity of cystitis in response to increasing doses of acrolein in female C57BL/6N (C57) mice, with further studies to compare the severity of acute acrolein-induced cystitis among C57, C3H/HeJ (HeJ), and C3H/OuJ (OuJ) strains of mice, as chemical cystitis produced by the systemic administration of cyclophosphamide is thought to result from renal excretion of hepatic metabolites, particularly acrolein.
- Publication
BJU international, 2007, Vol 99, Issue 6, p1523
- ISSN
1464-4096
- Publication type
Journal Article
- DOI
10.1111/j.1464-410X.2007.06773.x