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- Title
Ammonia-dependent differential regulation of the gene cluster that encodes ammonia monooxygenase in Nitrosococcus oceani ATCC 19707.
- Authors
El Sheikh, Amal F; Klotz, Martin G
- Abstract
Molecular analysis of the ammonia monooxygenase-encoding gene cluster in Nitrosococcus oceani revealed that the amo genes are differentially expressed from three promoters dependent on the external ammonia concentration. Whereas a distal amoRCABD operon promoter, pC1, is active only in the presence of ammonia, identified proximal amoC (pC2) and amoA (pA) sigma-70-type promoters are constitutive. Promoter region pC2 also contains a consensus sequence for binding of RpoN, usually involved in nitrogen starvation response. Additional regulation of transcript stability by anti-termination and mRNA degradation are proposed and discussed.
- Publication
Environmental microbiology, 2008, Vol 10, Issue 11, p3026
- ISSN
1462-2920
- Publication type
Journal Article
- DOI
10.1111/j.1462-2920.2008.01766.x