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- Title
Twice-weekly fluconazole prophylaxis in premature infants: association with cholestasis.
- Authors
Bhat, Vishwanath; Fojas, Milliecor; Saslow, Judy G; Shah, Sahil; Sannoh, Sulaiman; Amendolia, Barbara; Pyon, Kee; Kemble, Nicole; Stahl, Gary; Aghai, Zubair H
- Abstract
Fluconazole prophylaxis is effective in preventing invasive candidiasis in extremely low-birthweight (ELBW) infants. The authors previously reported an increased incidence of cholestasis with fluconazole prophylaxis in ELBW infants, which led to fluconazole prophylaxis being changed to a less frequent dosing (LFD) schedule of twice a week at their institution. The purpose of the present study was therefore to evaluate the effectiveness and safety of LFD fluconazole prophylaxis in preventing invasive candidiasis in ELBW infants.
- Publication
Pediatrics international : official journal of the Japan Pediatric Society, 2011, Vol 53, Issue 4, p475
- ISSN
1442-200X
- Publication type
Journal Article
- DOI
10.1111/j.1442-200X.2010.03286.x