We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Severe impulsiveness as the primary manifestation of multiple sclerosis in a young female.
- Authors
Lopez-Meza, Elmer; Corona-Vazquez, Teresa; Ruano-Calderon, Luis A; Ramirez-Bermudez, Jesus
- Abstract
Severe impulsiveness in the absence of apparent neurological signs has rarely been reported as a clinical presentation of multiple sclerosis (MS). An 11-year-old female developed progressive and sustained personality disturbances including disinhibition, hypersexuality, drug abuse, aggressiveness and suicide attempts, without neurological signs. She was given several unsuccessful psychopharmacological and psychotherapeutic interventions. At age 21, a diagnosis of MS was made, confirmed by imaging, laboratory and neurophysiological studies. Although unusual, MS may produce pure neurobehavioral disturbances. In the present case, widespread demyelinization produced a complex behavioral disorder, with features compatible with orbitofrontal and Klüver-Bucy syndromes.
- Publication
Psychiatry and clinical neurosciences, 2005, Vol 59, Issue 6, p739
- ISSN
1323-1316
- Publication type
Journal Article
- DOI
10.1111/j.1440-1819.2005.01446.x