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- Title
Des-gamma-carboxyprothrombin, alpha-fetoprotein and AFP-L3 in patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma.
- Authors
Durazo, Francisco A; Blatt, Lawrence M; Corey, William G; Lin, Jiing-Huey; Han, Steven; Saab, Sammy; Busuttil, Ronald W; Tong, Myron J
- Abstract
Hepatocellular carcinoma (HCC) is a common complication in patients with chronic viral hepatitis. Detection of HCC at an early stage is critical for a favorable clinical outcome. The study aim was to: (i) compare the levels of des-gamma-carboxyprothrombin (DCP), alpha-fetoprotein (AFP) and AFP-L3 in HCC patients and in chronic viral hepatitis patients without HCC; (ii) define the level of each tumor marker with the best sensitivity and specificity for HCC diagnosis; and (iii) to correlate the levels of these markers with respect to size and tumor burden.
- Publication
Journal of gastroenterology and hepatology, 2008, Vol 23, Issue 10, p1541
- ISSN
1440-1746
- Publication type
Journal Article
- DOI
10.1111/j.1440-1746.2008.05395.x