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- Title
Sp1-like transcription factors are regulators of embryonic development in vertebrates.
- Authors
Chengtian Zhao; Anming Meng
- Abstract
Sp1-like family is an expanding transcription factor family. Members of this family bind to the GC-box or GT-box elements in the promoter/enhancers and regulate the expression of the target genes. Currently, this family consists of at least nine members, which may act as a transactivator or a repressor on target promoters. Sp1-like transcription factors are expressed during development of vertebrate embryos in ubiquitous or tissue-specific manners and play various roles in embryonic development. This review mainly summarises their expression patterns and functions during vertebrate embryogenesis.
- Publication
Development, Growth & Differentiation, 2005, Vol 47, Issue 4, p201
- ISSN
0012-1592
- Publication type
Academic Journal
- DOI
10.1111/j.1440-169X.2005.00797.x