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- Title
Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty.
- Authors
Chou, W-Y; Yang, L-C; Lu, H-F; Ko, J-Y; Wang, C-H; Lin, S-H; Lee, T-H; Concejero, A; Hsu, C-J
- Abstract
Morphine consumption after a given surgical procedure can vary considerably. Studies show that single nucleotide polymorphism involving the nucleotide position 118 at exon 1 of the mu-opioid receptor gene (OPRM1) may play a role in mediating the effects of opioids. This study was performed to correlate the A118G polymorphism at OPRM1 with morphine consumption in patients undergoing total knee arthroplasty.
- Publication
Acta anaesthesiologica Scandinavica, 2006, Vol 50, Issue 7, p787
- ISSN
0001-5172
- Publication type
Journal Article
- DOI
10.1111/j.1399-6576.2006.01058.x