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- Title
N-methyl-D-aspartate receptor expression in parvalbumin-containing inhibitory neurons in the prefrontal cortex in bipolar disorder.
- Authors
Bitanihirwe, Byron Ky; Lim, Maribel P; Woo, Tsung-Ung W
- Abstract
Inhibitory neural circuits and the glutamatergic regulation of these circuits in the cerebral cortex appear to be disturbed in bipolar disorder. In this study, we addressed the hypothesis that, in the prefrontal cortex (PFC), disturbances of glutamatergic regulation of the class of inhibitory neurons that contain the calcium buffer parvalbumin (PV) via N-methyl-D-aspartate (NMDA) receptor may contribute to the pathophysiology of bipolar disorder.
- Publication
Bipolar disorders, 2010, Vol 12, Issue 1, p95
- ISSN
1399-5618
- Publication type
Journal Article
- DOI
10.1111/j.1399-5618.2009.00785.x