We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Further support for association of the mitochondrial complex I subunit gene NDUFV2 with bipolar disorder.
- Authors
Xu, Chun; Li, Peter P; Kennedy, James L; Green, Marty; Hughes, Bronwen; Cooke, Robert G; Parikh, Sagar V; Warsh, Jerry J
- Abstract
The nuclear-encoded mitochondrial complex I subunit gene, NDUFV2, has been implicated in the pathogenesis of bipolar disorder (BD) in Japanese by virtue of association of variants in its promoter with BD and decreased NDUFV2 messenger ribonucleic acid (mRNA) levels in B lymphoblasts (BLCL) in BD patients compared to controls. We sought to determine if these same changes occur in non-Japanese populations and, if so, their relationship to altered basal intracellular Ca(2+) ([Ca(2+)](B)) in BLCL from BD patients.
- Publication
Bipolar disorders, 2008, Vol 10, Issue 1, p105
- ISSN
1398-5647
- Publication type
Journal Article
- DOI
10.1111/j.1399-5618.2008.00535.x