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- Title
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder.
- Authors
Blumberg, Hilary P; Fredericks, Carolyn; Wang, Fei; Kalmar, Jessica H; Spencer, Linda; Papademetris, Xenophon; Pittman, Brian; Martin, Andres; Peterson, Bradley S; Fulbright, Robert K; Krystal, John H
- Abstract
Abnormalities in volumes of the amygdala have been reported previously in adolescents and adults with bipolar disorder (BD). Several studies have reported reduced volumes in adolescents with BD; however, both decreases and increases in volumes have been reported in adults with BD. Understanding of potential developmental contributions to these disturbances in morphology of the amygdala has been limited by the absence of longitudinal data in persons with BD. Here we use a within-subject longitudinal design to investigate whether amygdala volume abnormalities persist in adolescents and young adults with BD over a time interval of approximately 2 years.
- Publication
Bipolar disorders, 2005, Vol 7, Issue 6, p570
- ISSN
1398-5647
- Publication type
Journal Article
- DOI
10.1111/j.1399-5618.2005.00264.x