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- Title
Total serum tryptase levels are higher in young infants.
- Authors
Belhocine, Wahib; Ibrahim, Zouher; Grandné, Véronique; Buffat, Christophe; Robert, Philippe; Gras, Delphine; Cleach, Isabelle; Bongrand, Pierre; Carayon, Pierre; Vitte, Joana
- Abstract
Mast cells participate in immune defense and allergic disease. At baseline, serum tryptase levels primarily reflect mast cell burden, while mast cell degranulation leads to granule tryptase release, which may be detectable as a transitory elevation of serum tryptase levels. Thus, mast cell burden and mast cell activity are reflected by serum tryptase levels, but reports are scarce in infants under 1 yr. We aimed at defining levels of total serum tryptase levels in this population.
- Publication
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2011, Vol 22, Issue 6, p600
- ISSN
1399-3038
- Publication type
Journal Article
- DOI
10.1111/j.1399-3038.2011.01166.x