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- Title
Porphyromonas gingivalis mediates the shedding and proteolysis of complement regulatory protein CD46 expressed by oral epithelial cells.
- Authors
Mahtout, H; Chandad, F; Rojo, J M; Grenier, D
- Abstract
Human cells express membrane-bound complement regulatory proteins to prevent complement-mediated autologous tissue damage. In this study, we hypothesized that Porphyromonas gingivalis, the major etiological agent of chronic periodontitis, causes the shedding or proteolysis of the complement regulatory protein CD46 expressed by oral epithelial cells.
- Publication
Oral microbiology and immunology, 2009, Vol 24, Issue 5, p396
- ISSN
1399-302X
- Publication type
Journal Article
- DOI
10.1111/j.1399-302X.2009.00532.x