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- Title
Mechanisms of inhibition by fluoride of urease activities of cell suspensions and biofilms of Staphylococcus epidermidis, Streptococcus salivarius, Actinomyces naeslundii and of dental plaque.
- Authors
Barboza-Silva, E; Castro, A C D; Marquis, R E
- Abstract
Fluoride is known to be a potent inhibitor of bacterial ureases and can also act in the form of hydrofluoric acid as a transmembrane proton conductor to acidify the cytoplasm of intact cells with possible indirect, acid inhibition of urease. Our research objectives were to assess the inhibitory potencies of fluoride for three urease-positive bacteria commonly found in the mouth and to determine the relative importance of direct and indirect inhibition of ureases for overall inhibition of intact cells or biofilms.
- Publication
Oral microbiology and immunology, 2005, Vol 20, Issue 6, p323
- ISSN
0902-0055
- Publication type
Journal Article
- DOI
10.1111/j.1399-302X.2005.00228.x