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- Title
HLA analysis of the Parsi (Zoroastrian) population in Pakistan.
- Authors
Mohyuddin, A; Mehdi, S Q
- Abstract
The Parsis of Pakistan are descendants of Zoroastrians from Iran who fled to Gujarat in India after the Arab invasion in 900 AD. A small group eventually migrated from India to Karachi in Pakistan. In this study, the Parsis from Pakistan were analyzed at the HLA-B, -C, -DRB1 and -DQB1 loci using the polymerase chain reaction with sequence-specific primers (PCR-SSP). The most common alleles at the HLA loci were HLA-B*35 (15.9%), HLA-Cw*0602 (21.4%), HLA-DRB1*11 (23.0%), and HLA-DQB1*02 (24.7%). Data analysis suggests that the Parsis of Pakistan and India descended from the same stock and may have the closest ancestry with Jewish and Italian populations.
- Publication
Tissue antigens, 2005, Vol 66, Issue 6, p691
- ISSN
0001-2815
- Publication type
Journal Article
- DOI
10.1111/j.1399-0039.2005.00507.x