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- Title
Carrier-bound nonallergenic Der p 2 peptides induce IgG antibodies blocking allergen-induced basophil activation in allergic patients.
- Authors
Chen, K-W; Focke-Tejkl, M; Blatt, K; Kneidinger, M; Gieras, A; Dall'Antonia, F; Faé, I; Fischer, G; Keller, W; Valent, P; Valenta, R; Vrtala, S
- Abstract
More than 90% of house dust mite-allergic patients are sensitized to the major Dermatophagoides pteronyssinus allergen, Der p 2. The aim of this study was to develop and characterize an allergy vaccine based on carrier-bound Der p 2 peptides, which should allow reducing IgE- and T-cell-mediated side-effects during specific immunotherapy (SIT).
- Publication
Allergy, 2012, Vol 67, Issue 5, p609
- ISSN
1398-9995
- Publication type
Journal Article
- DOI
10.1111/j.1398-9995.2012.02794.x